Supreme Pharmacist System

Chapter 91: Prions

Then Zhou Wen spent 200 points to learn the formula of biological anti-wrinkle cream.

Zhou Wen looked it up, and it was indeed good. As expected, he also needed to buy a special biological enzyme additive from the system store.

Leave this aside for now.

After calming down, Zhou Wen thought about it for a while and upgraded the pathology to LV2.

Pathology and pharmacology are complementary to each other. From the perspective of pharmacy, only by knowing more about the causes, mechanisms, development rules and morphological structure of the body during the disease process can we better study drugs.

With the upgrade of [Pathology], a lot of knowledge poured into Zhou Wen's brain.

The pathological knowledge stored in the brain quickly became alive.

In the past, I only knew one thing and didn't know the other, but now I have a deeper understanding.

Combined with pharmacology, he has really become a brilliant doctor now.

And a general practitioner.

He understands the causes and treatment options for the vast majority of common ailments.

Such as inflammation, cardiovascular disease, respiratory disease, digestive system disease, lymphatic hematopoietic system disease, immune disease, urinary system disease and so on.

Zhou Wen was so excited that he almost jumped up.

It may be difficult for outsiders to understand his current mood.

Like a scumbag who knows the content of the college entrance examination in advance, and then memorizes all the knowledge points and answers to the questions in advance, and waits for life to counterattack, what does it feel like?

It's so refreshing, is there anything?

And Zhou Wen "recited" not only the answers of the college entrance examination, he even "recited" the answers of the college entrance examination.

This feeling of taking shortcuts in life made Zhou Wen's three hundred and sixty pores stretch out.

Now he really wants to find someone to see a doctor, such as orthopedics...

Sunday morning.

It may be because of the rain yesterday, but the weather today is exceptionally good. The fiery red sun rose from the sky early, scorching the earth, and the air gradually began to heat up.

At eight o'clock in the morning, Zhou Wen took the bus to Tianhai Intellectual Property Agency Co., Ltd. on Jianghai Road.

I met Meng Xiang, the general manager, in the office.

Meng Xiang is very young, only in his early 30s, with a cropped cut, wearing a red striped shirt + black trousers, and a pair of gold-rimmed glasses on the bridge of his nose.

"Mr. Zhou, hello~"

"Hello, Manager Meng."

The two exchanged simple greetings, and then sat down separately.

Zhou Wen took out the printed patent application specification from his computer bag, "Manager Meng, take a look."

"Okay." Meng Xiang took a thick stack of instructions, pushed the frame on the bridge of his nose with his middle finger, and then turned to the first page to read.

Meng Xiang looked quickly, ten lines at a glance.

Like those process flow charts, formulas, etc., just skip it.

Thirty-five thousand words, plus picture formulas, etc., a total of nearly 30 pages, and Meng Xiang saw the end in five minutes.

Those things will naturally be reviewed one by one in the future. What he needs to know is, what is the result of such a long patent specification?

Where is it awesome?

"Product effect description: After refining and improving this technological process, the effect of the powerful version of sildenafil tablets will be increased by 200% to 300% on the basis of the original."

Meng Xiang: "..."

Meng Xiang felt extremely speechless.

He didn't know what to say.

Seeing that the other party is the classmate of the chairman's precious daughter, he rushed to the company to wait for the other party for more than an hour on Sundays, but what he waited for was this Arabian Nights prescription...the process.

What international joke?

Who do you think you are, still improving sildenafil?

Pfizer Pharmaceuticals of the United States,

Since the discovery of the effect of sildenafil in the treatment of ED in the early 1990s, hundreds of pharmaceutical engineers have invested in research and development.

The technological process has long been tried and tested.

You casually say that you have improved other people's technological process, and the effect has been increased by 200%~300%.

Do you think highly of yourself, or do you look down on Pfizer's pharmaceutical engineers too much?

"Ahem~" Meng Xiang coughed and said, "Well, Mr. Zhou... I don't think it is necessary to apply for this patent."

Zhou Wen wondered, "Why?"

Meng Xiang stretched out his hand and pushed down the frame, and said euphemistically, "I think it's impossible to patent this technological process.

You have to know that it took Pfizer nearly 10 years to develop sildenafil, and the process has been continuously improved for 20 years after it went on the market. It is not easy to surpass them. "

Zhou Wen smiled.

Without the results of clinical trials, anyone who reads the description of this patent application will feel that it is fantasy.

He didn't argue, and said with a smile: "What Manager Meng said is true, but I still want to register a patent."

Meng Xiang knew that a person who could write a 35,000-word patent application description would not be able to give up the idea of ​​​​registering a patent with just a few words, so he didn't try to persuade him.

"Since you insist, then do as you say."

Zhou Wen asked, "What about the fee?"

Meng Xiang thought about it for a while and said: "To be honest, if calculated according to the value in your patent specification, the agency fee is very expensive, but you...

Let's do this, add all the expenses together, and you can pay a total of 150,000. "

"150,000... is still a friendly price. The prices of these top agency firms are really expensive."

Zhou Wen said something secretly in his heart, and asked, "Do you think this is okay? I will pay 10,000 first, and the rest will be paid later?"

Meng Xiang nodded, "Yes."

Then the two parties signed an agency agreement, and Zhou Wen gave Meng Xiang a copy of his ID card.

Alipay then transferred 10,000 yuan to Tianhai's company account.

Even if the agency matters are settled.

The rest will be handled by Tianhai Office. He only needs to wait for the patent certificate.

Zhou Wen got up to say goodbye.

Meng Xiang sent him all the way to the elevator entrance, and turned back to the office after watching the elevator go down.

On the way, he picked up the phone and made a call.

"Hey, miss, it's been done... His patent... a total of 150,000..."

Just as Meng Xiang mentioned the price, a roar came from the phone, "What, 150,000, so much?"

Meng Xiang smiled wryly: "This price is already very cheap. If calculated according to the market price, the agency fee is at least 1 million."

"Don't be so dark-hearted, okay? How can he have so much money? And you said that it is impossible to succeed, why do you want to cheat other people's money... just 10,000."

"I didn't cheat him for money...and I've already signed the contract, so it's not easy to change."

"Then I don't care, you can figure it out yourself."

"I... beep..." Meng Xiang was about to speak when the phone was hung up.

Meng Xiang looked at the hung up phone and said depressedly: "It's true that the girl's elbow is turned outward. She must never have a daughter in the future."

...

As soon as Zhou Wen arrived downstairs, he received a call from Yang Liqun asking him to go to the testing center.

Zhou Wen hurried to the testing center.

Yang Liqun handed over an electrophoresis test report, "Take a look."

"What's the matter?" Zhou Wen took a look and found that it was a very rare "prion".

Knowledge about prions quickly emerged in Zhou Wen's brain.

Strictly speaking, "prion" is not a virus, it is a toxic biomolecule that only contains protein, but no "nucleic acid", so it is also called "prion protein".

Prion is currently recognized as a misfolded protein in the world, and there is no generally accepted conclusion on its three-dimensional structure.

As a self-replicating peptide chain, prion protein may be an ancient and primitive biological molecule than nucleic acid chain.

It may have been an accidental "amino acid combination" that gave it the initial characteristics of life such as "replication".

However, although it is not a virus, the horror of prions is no less than that of viruses, or even worse.

The famous "mad cow disease" (CJD) is caused by prions.

Many neurological diseases, such as "Alzheimer's disease" and "Parkinson's disease", are inextricably linked with prions.

The clinical manifestations of such diseases are generally central nervous system diseases such as ataxia, tremor (shaking hands), unstable posture, dementia, hypersensitivity, and abnormal behavior.

Yang Liqun said: "The clinical manifestations of this case are very special, he often laughs uncontrollably..."

——

ps: Sorry, please...

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