Supreme Pharmacist System

"It is said that Huanyu has completed the development of the active compound and is currently undergoing pharmacological evaluation."

Lang Yongfeng, executive director of Tianfeng Zhengda, looked at the paper data on the table and said.

As a pharmaceutical company that started from generic drugs, Tianfeng Zhengda has also invested a lot of money in new drug research in the past two years.

However, the development of new drugs cannot produce results in a short period of time, nor does it mean that results will definitely be produced.

Even in the clinical trial stage, as drug evaluation becomes more and more difficult, fewer and fewer new drugs can pass all phase 3 clinical evaluations and be launched on the market.

Part of the reason is that it is becoming more and more difficult to develop new drugs with better comprehensive evaluation than existing drugs on the market. For example, last year, the FDA (US Food and Drug Administration) only approved 35 new drugs.

For example, a second-class new drug that Tianfeng Zhengda invested heavily in research and development before has entered the second phase of clinical trials, but it died prematurely. The 75 million US dollars invested in the early stage was all in vain, which is very miserable.

Of course, drug research and development is also an industry with high investment and high risk accompanied by high returns.

Once the drug is successfully marketed, the return is also amazing.

There is a term in the industry called "blockbuster", which refers to a drug with annual sales of more than $1 billion.

An extreme example is Pfizer's patent-protected lipid-lowering drug Lipitor. In 2010, global sales reached an astonishing $10.133 billion.

Hearing Lang Yongfeng's words, a middle-aged man with four eyes pushed the frame on the bridge of his nose and said, "This company's research and development capabilities are very strong, and it is almost a certainty that it has entered the clinical trial stage; I just don't know how much success it will have. ?”

Another man with three beards, smoking a cigarette, said: "I think you are all worrying about nothing. What is the point of this? The clinical trial has not even started. There is nothing to worry about."

Lang Yongfeng shook his head and said: "You are wrong, I am not worrying unnecessarily, He Junfeng, the chief scientist of Type B of the Academy of Sciences, has joined their team, do you know what this means?

You may not know He Junfeng, he is very proud. Mr. Xie wanted to invite him to be the chief expert consultant of our company, and even offered him an annual salary of tens of millions + bonus equity, but he didn't even look at it, so he just refused. .

The fact that he can join the Universal Creature only means that the other party must have something that he cannot refuse. "

The middle-aged man with four eyes said, "Boss Lang means... Huanyu Biology has made a breakthrough discovery in the treatment of hepatitis B?"

Lang Yongfeng nodded affirmatively: "Yes!"

...

Kapok City, Sichuan Province, Ruiyang Pharmaceutical Factory, Science and Technology Park Avenue.

Ruiyang is just a very small pharmaceutical factory, mainly engaged in the processing of preparations. There are only more than 30 employees in total, and there are also four technicians.

These technicians, in addition to being responsible for the daily production in the factory, will also conduct some drug research.

Mainly painkillers.

The reason why they studied painkillers was mainly because of the boss and technical director Fu Le.

Fu Le used to be an anesthesiologist. He left the job seven years ago due to some incidents. He entered the pharmaceutical industry by accident.

Then I started researching painkillers as a personal hobby in my spare time.

But today, Ruiyang Pharmaceutical Factory is about to close down. Because of the continuous shrinkage of the contract processing business, the factory can no longer sustain itself and has to close down.

At this time, the four technicians in the laboratory looked at the packed experimental equipment on the ground with expressions of reluctance, but it was useless to reluctance. They still had to live and had to find another way of life.

It's just a pity for the boss Fu Le, he is a person with ideals and sentiments, and he has paid practical actions for his dreams.

"Let's go, say goodbye to old Fu."

"Walk……"

Several people looked at the experimental instruments on the ground again, and left the laboratory after sighing.

In the office, a man in his forties with a thin face was calculating the company's property according to the documents given by the accountant.

After some calculations, after deducting various expenses, after selling all the equipment, not only was there no penny left, but there was also a debt of more than one hundred thousand.

This man is naturally Fu Le, the owner of Ruiyang Pharmaceutical Factory.

Fu Le smiled wryly. It has been 7 years since May 2013, and he still has nothing and nothing accomplished in the end.

Fortunately, his wife divorced him a long time ago and took the child away with him, otherwise he would have no place to stand with him now.

"pretty good!"

Fu Le picked up his mobile phone and called the second-hand equipment recycler, "Hey Boss Zhang, come and get the equipment..."

After the phone call, Fu Le closed the computer and planned to leave, but at this moment, the phone on the desk rang.

"Hi, hello, who is it?"

A very contagious baritone voice came from the other end of the phone, "Excuse me, are you Mr. Fu?"

Fu Le: "Yes, I am, who are you?"

Baritone: "I'm Tong Miao, the assessor of the Universal Bioscience Research Foundation. After we received your application, we have evaluated your company and experimental projects. Now I have some questions to ask you. Is it convenient for you now? "

"Huanyu Foundation?" After hearing the other party's words, Fu Le was taken aback for a moment, and then suddenly remembered that he seemed to have filled out some application form last month.

"By the way, the Universal Scientific Research Sponsorship."

Fu Le suddenly remembered.

Last month, he applied for a 1 million scientific research grant from the Universal Research Foundation.

Although I knew there was little hope, I was desperate at the time, so I filled in some information in the hope of just in case.

I didn't expect the Foundation to call me.

"Well, you ask." Unknowingly, Fu Le became respectful even in his words.

There is no way, who made the other party the God of Wealth? Whether Rui Yang can continue to maintain it depends on whether the other party lets go.

Tong Miao: "The whole call was recorded."

Fu Le: "Yes! Got it."

Tong Miao: "Okay, now it's officially started. I read in the application instructions that you have been an anesthesiologist for 11 years. Why didn't you do it in the end?"

Fu Le: "Because of relationship problems."

Tong Miao: "Then why did you think of studying painkillers?"

Fuller: "Because I believe that any real anesthesiologist would like to develop an analgesic that can effectively block pain without producing euphoria."

Tong Miao: "I don't quite understand, can you explain the reason in detail?"

Fu Le: "Okay! It sounds a little nonsensical. Analgesics are the job to relieve pain. Wouldn't it be better to provide euphoric comfort as well?

However, countless problems in the world stem from this "feeling good" feeling.

The word euphoria sounds high-sounding, but it is almost a two-in-one with the words "drinking", "d addiction", and "withdrawal reaction".

You may not know that a sad fact is that the analgesics that save hundreds of millions of cancer patients and severe pain, and are necessary for surgery, are being abused by addicts who pursue pleasure, and become "D products that are discolored" ".

The most commonly used analgesics for Linchuang are opioids. The opioid here is actually a euphemistic English translation, but the exact name is Y tablets.

Opioids originally referred to the resinous exudates extracted from poppy pods. Later, with the development of the chemical industry, they transitioned to artificial semi-synthetic and fully synthetic narcotic and analgesic drugs.

Commonly used clinically include morphine, buprenorphine, fentanyl, demerol, tramadol, methadone, etc. There are also various painkiller plasters and emulsions that also contain opioids.

As a strong analgesic, opioids enter the nervous system and bind to opioid receptors, which can quickly increase the body's pain threshold, reduce the body's perception of pain, and produce a strong analgesic effect.

But its other function is to make users feel a special sense of euphoria and a very happy and comfortable feeling, which is the root cause of the abuse of this type of drug.

Euphoria and addiction are almost inseparable. Extraordinary pleasure is pleasure and hell.

Being cool is not a problem, the problem is to keep being cool.

The subjective desire of human beings to seek intense stimulation is almost endless.

After experiencing a pleasure far beyond imagination, any ordinary stimulus is like tickling. Once the pleasure threshold is raised, it is difficult to suppress it.

The so-called transition from extravagance to frugality is difficult, and wanting to be happy after being happy is an addiction.

A word of addiction has ruined countless people.

As an anesthesiologist, I am very sad to see that many drugs that were originally invented to benefit mankind are abused as D products. serious crimes committed.

For example, chloramine-tong is an excellent short-acting analgesic in the field of pediatric anesthesia, with fast onset of action, fast metabolism, and the function of dissociative anesthesia.

But it is now called K-- powder, no one knows that it used to be a good helper for anesthesiologists.

Because of this, I especially hope to clarify the entire pain signal as soon as possible, and develop an analgesic that can effectively block pain without relying on opioid receptors..."

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