Rebirth of the God-level Xueba

【Your every click, every collection, every recommendation, and every subscription is an important encouragement and support for Zhidiao Village】'

***********************************

【Rebirth God-level Scholar】Creation page:

***********************************

[Rebirth God-level Scholar] Total serial post!

***********************************

[Signing in is the embodiment of honor and strength, I hope you don't forget to click the sign in the upper right corner while watching the update]

***********************************

"This is the first priority project. Since the establishment of my laboratory several years ago, this is the most important project." Yang Rui convinced everyone in the laboratory, and also convinced the lawyers who came from Hong Kong.

Of course, a lawyer is paid and has to work no matter what, but whether he understands the importance of the project also determines the way he works.

Big-name lawyers can make money wherever they are, and they will pick jobs like taxi drivers on rainy days. Simple patents with no benefits can be done more easily. This kind of patent may not be encountered once in a lifetime. The lawsuit challenge expired, and the leak-proof patent that Yang Rui expected was time-consuming and labor-intensive. If you want someone to help you do it seriously, you have to prove that your patent is worth doing.

Lawyer Yue Ting led two assistants with great professionalism and listened carefully. He has been a patent attorney for more than 30 years, and he himself graduated from the Department of Physics of the University of Hong Kong. His background in science has led him to the path he is in today. Yang Rui deliberately speaks simply, so he can understand most of the content. of.

After about half an hour, Yue Ting asked to see X-rays.

DNA cannot be seen with the naked eye, nor can it be seen with an ordinary microscope. In fact, it is idle to see it, and you do not know it.

28 base pairs of DNA, even if you ask it "who are you", you will not receive an answer.

To prove the success, you have to use the hybridization signal on the X-ray film.

Yang Rui first looked at another company lawyer next to him.

The company lawyer also came from Hong Kong, but he was a long-term contracted company lawyer of Huarui and Yang Rui's own person. After the latter nodded, Yang Rui went to get the X-rays.

In fact, there is nothing to hide. This is something that belongs to the professional category, and it cannot be copied.

The reason why Yang Rui redid the experiment was to have these seemingly useless proofs.

Otherwise, he can just copy the paper directly.

However, if you just copy papers, you will not be able to pass the round after round of academic review.

Many papers that change the world are very short - Tu Youyou's Nobel Prize-winning paper is titled "A Novel Sesquiterpene Lactone-Artemisinin", signed by the Artemisinin Structure Research Collaborative Group, and the full text is only one page . The DNA double helix written in every student's textbook also won the Nobel Prize for Watson and Crick, and the full text is only half a page.

Long papers are rare, and such short papers are also rare.

At the very least, it is difficult to copy, but applying for a patent cannot be as detailed as a paper.

Applying for a patent is just chatter, how come there are so many.

Some large companies, in order to apply for a patent, will list hundreds of parallel patents,

All to protect the core patents in the middle.

Therefore, many large companies have tens of thousands of patents a year, not that they really have tens of thousands of patents. It is very good to have thousands of patents, and the rest are patents that are popular.

However, patents that are popular also need to be carefully written, which will consume the time of the lawyer and the patent office. In the final analysis, it will cost money.

And it's very expensive.

This is especially true for mainlanders in 1984.

Yue Ting calculated a number in his heart and shook his head in his heart.

Of course, he would not say to Yang Rui, "You don't need to get patents like this for your research." If he was a white man, he would have made money first without saying a word.

Facing Yang Rui who was in the mainland, Yue Ting wanted to save some money for Yang Rui, but he also felt that it was too troublesome, thinking about it: "I understand what you just said, but I think the cost is a bit high, especially what you asked for. Applying for multiple patents in one go and applying for patent protection will cost a lot of money, at least millions of dollars, and because of the salary of other lawyers, the amount of this part cannot be determined , just more and less."

On the one hand, he was scaring Yang Rui, and on the other hand, he was telling the truth. If he followed Yang Rui's request, he would have to pay millions of dollars, nothing less.

If you encounter a patented submarine, you have to fight a lawsuit.

And if you want to make your own patented submarine, you have to spend a lot of money.

Patent barriers have always been something that big companies like. Small companies can only do this with confidence, which is an act of self-defense.

Yang Rui has carried out a series of patent application activities for the patent of coenzyme Q10, but the requirements at that time were more than an order of magnitude different from those now. The same goes for the strength and price of the lawyers brought in.

However, coenzyme Q10 is only a billion-dollar market, and Zeneca's profit is 100 million dollars, and the patent owner's profit is millions of dollars.

But it was a terrible monster. It may be the first blockbuster in the field of biotechnology, and eventually created a market worth 100 billion U.S. dollars. Historically, the technology patents represented were worth 3 billion U.S. dollars.

And that doesn't include the controversial high-temperature-stable polymerase.

Now, Yang Rui has made up for the shortcomings of high-temperature-resistant polymerases, and his profits may rise sharply.

In his heart, Yang Rui wanted to apply for the patent at any cost.

However, no matter the cost has always been a false proposition, money is the last word, and funds will always be the bottleneck.

Yang Rui didn't have a million dollars in his hand.

Recently, the Huarui laboratory has been spending money like water, and he still dare not cut it off... Although the experiment can apply for a patent, it is still a long way from the complete academic completion, and it still needs to continue to invest, and in the short term If there is no return, he will have to apply for more patents in the future, including patents, and maybe Huang Mao and others have made achievements, and there will be money everywhere.

Enterprises will have capital chain problems, and laboratories will also have problems.

And Yang Rui's income is only the dividends from Zeneca.

Once every three months, now there are millions of dollars when it is more, and only seven or eight hundred thousand when it is less.

If this money is used for personal life, the wealthy don't know how to spend it, and they can buy a Ferrari in a few days.

However, I don't know how many things are more expensive than Ferrari in the laboratory...

Yang Rui also held his forehead and remained silent.

"Mr. Yang Rui, you should also pay attention to the issue of patent disclosure. Among the major patent countries in the world, only a few countries, such as the United States, do not have a patent disclosure system. But if you want to apply for patents in multiple countries, you need to disclose the patent content. Anyone can search for it, and once you find it, your technology may face competition." Yue Ting knew that Yang Rui's research had not been fully completed, so he wanted to persuade Rui Rui from this perspective.

Yang Rui said without even thinking about it: "It is impossible for others to do it faster than me. Even if it is made public, they will be too late."

"But disputes can add to costs."

"There's no way around that. I can't stop applying for a patent just because of this. Mr. Yue, for the project, I would rather go bankrupt and do it. Please take care of me..."

After Yang Rui said so, Yue Ting, as a lawyer, only nodded and said, "Okay, I will complete the preparation and application work as soon as possible. You will be able to check the public records in a month at most."

"That is to say, I still have at most one month before the patent is published?"

"Maybe only twenty days, if our application goes well. We are professional patent lawyers, and the speed is much faster than ordinary patent firms." Yue Ting is quite proud of this.

Yang Rui nodded slightly, and said: "So far, I have carried out this project independently. Now that the original stage is over, the next step is to enter the verification and improvement stage. I am going to let the employees of the laboratory intervene. Is this appropriate? It will not affect Go to the patent application work."

"Of course not." Yue Ting laughed.

Huarui's company lawyer also explained: "Employees have signed strict confidentiality agreements and have also given up related claims. You can rest assured."

"I hope that both of you will conduct a re-inspection independently."

The company lawyer was a little unhappy, but he could only say, "I will give Mr. Yue a copy."

"Independent review, if you have any problems, please report to me alone. It doesn't matter if there are loopholes in the previous contract. We can make up the signing now. I don't want other loopholes to appear after other people intervene."

"You should really be a lawyer." Yue Ting didn't take Yang Rui's cautiousness seriously, but he understood Yang Rui's importance to this matter, and corrected his attitude.

For patent lawyers, they do not need to judge the value of patents, the attitude of the employer is everything. If the employer thinks he invented the stinky law, the job of the patent attorney is to protect the stinky law, not to rate the stinky law.

"Don't be afraid of wasting paper, the contract must be strict." Yang Rui urged again.

This is a Nobel Prize-level achievement, and I don’t know how many laboratory colleagues have filed lawsuits for it. When Waksman discovered streptomycin, he was sued by his Ph.D. The statement recognizes that Saz is the co-discoverer of streptomycin in the legal and scientific sense, and grants Saz a foreign patent income of 120,000 US dollars and 3% of the patent income...

The academic circles naturally disagree with this. Saz is nothing more than a head dog under Waxman, and there are 50 scientific research dogs in Waxman's laboratory. When Waxman adopted After the correct screening, any one of the fifty scientific research dogs may find streptomycin, sooner or later.

The later Nobel Prize was nothing like Saz. The so-called co-discoverer in the scientific sense was not recognized by any scholar at all.

In the end, Saz had no place in academia, but he did take the patent share.

Yang Rui didn't want such a thing to happen to him.

When he was a graduate student, there were actually many graduate students and doctoral students like Saz around him. When everyone is drunk, they will say: "I did all the work, but the results belong to the boss, and the first author belongs to the boss...it's not fair!"

Yang Rui is a supporter of this injustice. Laborers are worthy of respect, but laborers are not competitive and have no right to be rewarded for the achievements of intellectual activities.

A manual labor dog in the scientific research world is not even considered a human being, so how can he be eligible to win prizes and money!

Since Saz and Waxman, laboratories in various countries have also updated laboratory regulations and contracts, and there are countless templates. Yue Ting and the company's lawyers understood Yang Rui's psychology and went to work separately.

That night, Yue Ting and the company's lawyer met with Yang Rui respectively to revise the contract.

The next morning, after Huang Mao and others re-signed the contract, they began to participate in the project.

It is true that they have not participated in the discovery, and it is only natural to give up the relevant rights. In addition, they will not be aware of the powerful potential like Yang Rui.

At Yang Rui's request, in addition to Huang Mao and Tu Xian continuing their original project, Wang Xiaoyun, Wei Zhenxue, Li Wenqiang, Duan Bo, and Zhang Xuetong all joined the project team one after another.

Their job is to complete an experiment with the highest "gold standard".

The gold standard calls for the amplification of a single copy of a gene from 1 microgram of human DNA.

This will be a long and arduous process, which is true for the first-generation technology, and it is also true for Li Wenqiang and others who have just come into contact with it, and it is especially true for Zhang Xuetong, who is responsible for the production of oligonucleotides and other raw materials.

Yang Rui began to write papers independently.

Unlike the potassium ion channel project, the technology is simple, simple and perfect, and has a long history.

...