I Don’t Want to Win Lying Down

"I'm mad at me!"

"Obviously, I am so young... why have I become an aunt?" Yang Xiaoman went crazy shopping for cosmetics in the online mall. When he was just walking, he was hurt by a high school girl. She was obviously much younger than her. The little girl didn't have long eyes, so she called Auntie when she came up.

"Damn..."

"Okay!" Xu Mang sat on the bed, glanced at Yang Xiaoman's tablet, and said with a look of horror: "You...your shopping cart...has more than one million. Will you empty the shopping cart today?"

"how?"

"I'm upset and want to shop and vent?" Yang Xiaoman gave Xu Mang a white look, and said angrily: "My old lady, am I not beautiful? Are you telling me the truth, is the skin as tight as before? Is the appearance the same? As lovely and touching as before?"

Damn it!

This is completely crazy!

Xu Mang was speechless. He didn’t think of an aunt that hurt so much. She kicked a Xiaoman who was at the top of her appearance to the bottom, completely hurting her self-esteem, but also... Xiaoman has always been a beautiful girl. As a result, one day the beautiful girl became an old aunt.

Hehehe...

What is going on here?

Why is there a hint of joy in my heart?

"Why are you laughing?" Yang Xiaoman said angrily: "Say it! Mother, am I the same as before?"

"Ok!"

"In fact, don't care about what others think of you, just feel beautiful." Xu Mang said with a serious face: "The good-looking skins are the same, but the interesting souls are one in a thousand. You are the best Xiaoman!"

However, facing Xu Mang’s chicken soup, Yang Xiaoman said with a disdain: "If someone says that you are not handsome at all and uglier than the Taibai cat who wrote the novel, what would you do?"

"fart!"

"Even though Xu Mang has admitted that he is the second handsome man in the world, I can't give up the position of the first handsome man just because of my approval." Xu Mang said angrily, "Don't use this metaphor in the future, my handsome is you. A dream that will never be touched in this life."

you...

I'm so angry, mother!

The anger reached its extreme, Yang Xiaoman went up and bit Xu Mang’s shoulder. Of course he didn’t dare to use force. If he bites blood, he won’t feel good in his heart, but he must bite his teeth to make this idiot grow long. memory.

"Damn!"

"Oh My God!"

"It hurts... Is it necessary for me to go?" Xu Mang said with an innocent look: "You are the most beautiful in my heart... Why bother to care about other people's opinions, saying you have too many things in your shopping cart ...How about husband, let me clean up for you?"

Yang Xiaoman was taken aback for a moment, and widened his eyes to look at Xu Mang. This guy is usually to death. This time he even asked to clean the shopping cart for himself. There must be fraud here!

"How do you clean up?" Yang Xiaoman asked.

"stupid!"

"Just choose batch delete directly." Xu Mang said with a grin: "Look... you can clean your shopping cart without spending a penny. My husband, I'm not smart? Are you surprised? Don't you? Don't kneel... If you really want to kneel, just kowtow by the way."

Yang Xiaoman: (*￣︿￣)

Fed up,

This **** is getting too much!

"My mother, I killed you today!"

"Look at the punch!"

(￣ε(#￣)☆╰╮o(￣絲￣///)

...

Life is like a book, don’t rush to the end to see if it’s worth reading, just taste it, you might as well skip to the last page, because every page leaves your own pain Memories.

"hiss!"

"Fuck... the waist is dead." Xu Mang was paralyzed on the bed, trying to get up, only to find that his waist was sore to the limit. At the moment of exerting force, it was as if a jack was pressing himself firmly on the bed, life and death. Can't move.

"Wife?"

"Wife?"

"Old witch?"

moment,

The bedroom door was opened, and Yang Xiaoman stood at the door, staring at Xu Mang angrily, yelling, "What did you call me just now?"

"..."

"My wife!" Xu Mang said awkwardly and politely: "Say, help me to tell the second grandfather, and say that I twisted my waist last night, and I will go to school in a few days. I will stay at home for a few days. By the way Call the mother-in-law and say that his son-in-law is going to eat stir-fried kidneys."

Yang Xiaoman blushed, and said angrily: "This little thing always tells mom to come...Her elderly people are usually very busy, so what...you want to eat stir-fried kidneys? I'm back from work. I passed by the hotel and asked the chef to make a plate for you. What else would you like to eat?

"No more."

"Exercise more in the future, it will always flash to the waist..."

for a long time,

Relying on his strong willpower, Xu Mang put on his underwear, washed briefly, and silently supported the wall to his study.

"what!"

"I'm going to die... this is just the beginning!" Xu Mang felt a trace of despair when he thought of the miserable life in which there will be another fifty years in the future. He was ruined in this whole life, and he was a little unwilling to think about it. .

Nothing more...

Solve the immediate problem first.

turn on computer,

Xu Mang flipped through the detailed information about the CRISPR system, not to mention the database of the Institute of Biochemistry and Cell Biology of the Academy of Sciences. It was really easy to use, but after reading it for a long time, he did not find any useful content.

immediately,

Xu Mang took a problem-based approach, such as asking for improved accuracy. Then, starting with accuracy, the CRISPR-Cas9 system cuts off the DNA duplex at a specific site in the genome, and then relies on the cell's own repair system to repair the damage. And perform gene editing.

but...

This repair system may insert or delete DNA bases where the genome has been cut, and is not entirely reliable.

"Ugh?"

"Is the problem here?" Xu Mang looked at the information, tilted his head and fell into contemplation. In the process, it seemed that researchers could not control the results of gene editing, and there might be differences between cells and cells.

about this issue,

Xu Mang searched for relevant information and found that biologists had added templates to guide genome editing in this process, but there were still some unsolvable problems.

Inserting a specific DNA sequence into the genome, DNA repair systems in many cells are more inclined to insert or delete a single or a few bases. This is particularly unreliable because it is impossible to replace a certain DNA fragment with Target sequence.

How to do?

That’s how I found the problem, but what should I do later?

At this time, Xu Mang's mind was blank. Except for the paste, it was all kinds of eating, drinking and having fun. There was not even a punctuation mark about breaking through the existing CRISPR system.

I...

It may not be possible!

"Hey?"

"Chenxi?" Xu Mang received the call from Chenxi and asked with a confused expression: "Are you going to break up again?"

"..."

"Brother Xu Mang...are you wishing me to break up with Tianmei? Then you can stand on the side and watch the theater?" Chen Xi said silently, "I'll greet you, do you have time tonight? Arrange it for you? How about going to have a bath together?"

"Yes, yes!" Xu Mang nodded, but his smile soon turned into a trace of sorrow, and he said helplessly: "How did your sister Xiaoman pass that level?"

"..."

"What about it?" Chen Xi said helplessly: "Sister Xiaoman knows that I will take you to take a bath, and I will be scolded to death by her."

"Ugh..."

"This woman is too violent." Xu Mang sighed, and said calmly: "I won't go...it just happens that I don't have much time. I just promised to help someone solve a problem, but now my mind is completely blank. Difficult..."

Suddenly,

There was silence over the phone.

"Brother Xu Mang?"

"Have you heard of Ollie give it?" Chenxi asked cautiously: "Very positive energy."

Xu Mang:? ? ?

What the hell?

Oreo cookies?

Under Chenxi's guidance, Xu Mang saw the legendary Ollie, but after reading it he was still confused.

perhaps...

I have completely separated from society, and my world is full of scientific research.

...

A few days later,

Fuda Department of Biology Building,

Because the arrival of one person broke the harmonious atmosphere here, Professor Xu Mang...he is back!

"Fuck!"

"Professor Xu seems to be in a molecular biology laboratory. I don't know what he is doing... Isn't he ready to develop a new AI technology?" A biology student rushed to his friends in horror: " That's awesome!"

"..."

"Don't tell me... it may create miracles again ~ www.wuxiaspot.com~ Another student standing beside said: "It's a pity... this time only three post-doctoral fellows in molecular biology were arranged. , To study with Professor Xu, it's a pity... what a pity! "

at the same time,

In the molecular biology laboratory,

Three young postdoctoral fellows stood in front of Xu Mang respectfully. Although the three had high prestige among the students, when facing Xu Mang, they seemed to be back when they were studying, and they felt like they were doing experiments with their supervisor for the first time.

tension!

Very nervous!

Xu Mang’s age is much younger than them, but it’s useless here. Xu Mang is the youngest Nobel Prize winner in natural sciences in history. He directly broke the record held by Lawrence Prague in 1915. Lawrence Prague at the time Prague is only twenty-five years old, and Xu Mang is more than three years younger than him.

"Speaking..."

"Do you know what to study this time?" Xu Mang asked curiously.

"Break through the existing framework of gene editing." said a postdoctoral fellow surnamed Chen: "Professor Xu...the three of us are pretty good in this field."

Xu Mang was stunned for a moment and smiled and said: "Not bad! Then it's up to you to play. This is a problem we need to solve. I printed a few copies, and you can take a look at yourself. If you have any ideas, the four of us It can be discussed."

moment,

The three young post-doctors got the information, opened it and looked at it. After only ten seconds, the three of them were completely confused.

This...

Solve the problem of replacing a certain DNA fragment with the target sequence?

Are you sure you can do it?

impossible!

......